Ketamine

Ketamine is a dissociative drug that has hallucinogenic effects. It distorts the perception of sight and sound. It can make a user feel disconnected from their body and environment. Ketamine can induce a state of sedation (feeling calm and relaxed), immobility, decreased pain, and amnesia (no memory of events while under the influence of the drug). It is abused for these dissociative sensations and hallucinogenic effects.

Ketamine is an FDA approved medical product for anesthesia. Ketamine injectable is approved for both human and veterinary use. Additionally, esketamine (the more potent S-enantiomer of ketamine) is approved for treatment-resistant depression and major depressive disorder with suicidal ideation as a nasal spray.

Drug Sheet.

Learn more.

Resources

Read the Ketamine Drug Fact Sheet.

Read the DEA-commissioned report on Trends in Ketamine Dispensing and Administration (Oct. 3, 2024)

Enforcement Cases

Allston Man Charged With Methamphetamine Trafficking
April 6, 2025

Riverside County Man Pleads Guilty to Trafficking 44 Kilograms of Cocaine and 10 Kilograms of Heroin
April 2, 2025

Repeat Offender Sentenced To 12 Years in Prison for Distributing Meth
Feb. 8, 2025

Middletown Meth Dealer Sentenced to 70 Months in Federal Prison
Oct. 30, 2024

Braintree Man Sentenced To 15 Years In Prison For Drug Trafficking And Money Laundering Charges
Oct. 29, 2024

New Jersey Man Arrested in Sales of Eight Guns, Cocaine and “Pink Cocaine” in Manhattan
Sept. 13, 2024

Sweeping DEA Operation Targets Pharmacy Burglaries and the Illegal Sale of Addictive Prescription Medications
Aug. 29, 2024

Five Defendants, Including Two Doctors, Charged in Connection with Actor Matthew Perry's Fatal Overdose Death Last Year
Aug. 19, 2024

Administrator Milgram's Statement on Charges Filed in Connection with Matthew Perry's Fatal Overdose
Aug. 15, 2024

Middletown Man Admits Trafficking Meth
July 16, 2024

Federal Indictment Alleges Alliance Between Sinaloa Cartel and Money Launderers Linked to Chinese Underground Banking
June 18, 2024

Repeat Offender Pleads Guilty To Distributing Methamphetamine
June 11, 2024

St. Louis Area Doctors Accused of Illegally Administering Ketamine
Jan. 11, 2024

St. Louis County Man Sentenced to Life in Prison for Dealing Fatal Dose of Fentanyl and Heroin
Oct. 24, 2023

Federal Jury Convicts St. Louis County Man of Dealing Fatal Dose of Heroin and Fentanyl
May 5, 2023

DOJ and Lincoln Pharmacy in Tacoma Settle Allegations the Pharmacy Failed to Follow the Controlled Substances Act
Feb. 28, 2023

Two Indicted After Drug Shipment Intercepted on Interstate 44 in St. Louis County
Feb. 17, 2023

Roseville Man Pleads Guilty to International Drug Trafficking Conspiracy in the United States and Canada
Dec. 13, 2022

Yale Agrees To Pay $308K To Resolve Allegations Of Violations Of Controlled Substances Act
Oct. 6, 2022

Dedham Veterinarian Agrees To Pay $15,000 Settlement To Resolve Allegations Of Inadequate Recordkeeping Of Controlled Substances
Sept. 21, 2022

Darknet Drug Trafficker Pleads Guilty to Conspiracy and Firearm Charges
March 7, 2022

Spokane Naturopath Agrees To Pay $47,700 Civil Penalty
Nov. 10, 2021

Department of Justice Announces Results of Operation Dark HunTor
Oct. 26, 2021

Albany Doctor Admits to Violating the Controlled Substance Act
Aug. 9, 2021

Doctor Sentenced to 38 months for Unlawful Drug Distribution and Identity Theft
May 14, 2021

Residents of Davis, Sacramento and Roseville Indicted for International Drug Trafficking
April 22, 2021

Indictment Charges Man for Trafficking Dangerous, Unusual Drug Mixtures of Heroin, Fentanyl, Tramadol and Methamphetamine
Oct. 5, 2020

Springfield paramedic charged with conspiring to distribute controlled substances
Sept. 30, 2020

Doctor pleads guilty to unlawful drug distribution and identity theft
Sept. 17, 2020

Trends in Ketamine Dispensing and Administration
July 27, 2020