Controlled Substance Ordering System (CSOS)

News & Updates

Please be advised that a scheduled system maintenance will take place on Friday, May 25, 2025, 6:00 PM to Monday, May 28, 2025, 8:00 AM (ET). During this time, systems may be temporarily unavailable or experience intermittent disruptions.

Virtual Training Sessions
CSOS Enhancements—Letter to Registrants (December 9, 2024)
CSOS Enhancements—Letter to Registrants (November 12, 2024)
CSOS Enhancements—Letter to Practitioners (October 16, 2024)
CSOS Enhancements—Letter to all other registrants (October 15, 2024)

DEA's Controlled Substance Ordering System (CSOS) is designed to provide services to DEA-registered pharmaceutical drug manufacturers, distributors, pharmacies, hospitals, and others to transmit customers’ orders electronically.

View the virtual training.

FAQ: Secure Hashing Algorithm (SHA) Transition

CSOS Questions & Answers

 

For Purchasers

CSOS allows for secure electronic transmission of Schedule I-V controlled substance orders without the supporting paper Form 222.

For Suppliers

DEA's Controlled Substance Ordering System (CSOS) allows suppliers to fill secure orders of electronic Schedule I-V controlled substances without the supporting paper Form 222.

Information for wholesalers, suppliers, distributors, and manufacturers:

For Developers

CSOS enabled ordering software, using a subscriber's CSOS digital certificate, allows a purchaser to place secure electronic orders for Schedule I-V controlled substances without a supporting paper Form 222.

Information for developers of CSOS enabled software systems:

 

[1] Microsoft Knowledgebase Article: http://support.microsoft.com/kb/968730

[2] Hotfix for Windows Server 2003 and Windows XP: http://support.microsoft.com/hotfix/KBHotfix.aspx?kbnum=968730&kbln=en-us