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Controlled Substance Ordering System
For Purchasers For Suppliers For Developers

DEA's Controlled Substance Ordering System (CSOS) allows suppliers to fill secure orders of electronic Schedule I-V controlled substances without the supporting paper Form 222.

Information for wholesalers, suppliers, distributors, and manufacturers:

bulleted item Learn about CSOS
bulleted item Review the Regulations
bulleted item Enroll in CSOS to report transactions
bulleted item Enroll in CSOS to purchase CII's
bulleted item Support your customers
Bullet Report a security concern
Certificate Support Guide - The Certificate Support Guide is intended to assist wholesalers in supporting their customers with the management of CSOS certificates.  Click here to get the latest version.
Latest News

Beware: Controlled Substance Ordering System (CSOS) Fraud Scheme

The Drug Enforcement Administration is warning the DEA registrant population of a fraud scheme in which scammers claim to be "Federal Agents" from the DEA CSOS Division who are requesting copies of DEA Registration(s), state license(s) and customer/supplier information. Please note that in order for registrants to utilize the Controlled Substance Ordering System (CSOS), applications and required supplemental information are only accepted via mail and are never requested without registrant initiation. If a registrant is seeking help with digital certificate download or renewals, a CSOS representative would ask the user for a security passcode only known to that user. Security concerns related to CSOS can be reported online https://www.deaecom.gov/support and/or by calling 1-877-DEA-ECOM (1-877-332-3266) toll free.