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Controlled Substance Ordering System
For Purchasers For Suppliers For Developers

DEA's Controlled Substance Ordering System (CSOS) allows suppliers to fill secure orders of electronic Schedule I-V controlled substances without the supporting paper Form 222.

Information for wholesalers, suppliers, distributors, and manufacturers:
bulleted item Learn about CSOS
bulleted item Review the Regulations
bulleted item Enroll in CSOS to report transactions
bulleted item Enroll in CSOS to purchase CII's
bulleted item Support your customers
Bullet Report a security concern
 Certificate Support Guide - The Certificate Support Guide is intended to assist wholesalers in supporting their customers with the management of CSOS certificates. Click here to get the latest version.

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Latest News

The Drug Enforcement Administration Controlled Substance (CSOS) program certificate retrieval services will be unavailable on Friday, January 27, 2023 from 6:00 P.M. EST through Sunday, January 29, 2023 6:00 P.M. EST due to maintenance.

If you have any questions, please contact the CSOS helpdesk at 1-877-DEA-ECOM (1-877-332-3266) toll free.

CSOS Helpdesk Team